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Non-Thermal Radio Frequency Stimulation of Tubulin Polymerization In Vitro: A Potential Therapy For Cancer Treatment

Open Journal of Biophysics

Background: 

The use  of radio frequency energy is an established technology for certain oncology therapies.  Direct inputs of radio frequency (RF) energy as thermal energy are applied to ablate tumors or catalyze secondary reactions in adjunct treatments against certain tumor types. Yet, other applications are being developed which take advantage of properties of RFs that impinge on biological proteins and cells without thermal effects. Here we report a proof-of-concept application of specific, digitally encoded, low power (non-thermal) radio frequency energy in an in vitro preparation of a tubulin polymerization assay.

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